Fresh from the success of their Boston-Cambridge Life Science evening, the PHASTAR team is at it again! This time PHASTAR will be hosting a Life Science Day near it's Alderley Park offices in Cheshire, UK.
The day will explore the theme of 'how statistical analysis and data science can enhance drug and diagnostic device development' and will feature talks given by PHASTAR staff and external experts.
Featuring talks from:
'What is Health Data Science? One biostatistician’s answer' by Professor Peter Diggle, Distinguished University Professor at CHICAS, Lancaster University Medical School.
'What sample size? 101 other ways statisticians influence trial design' by Andrew Lloyd, Head of Statistics - PHASTAR.
'Extracting value from real-world data: an example with wearables' by Professor Jennifer Bradford, Head of Data Science - PHASTAR.
'You've developed your AI tool - now how do we test it?' by Professor Jennifer Rogers, Head of Statistical Research - PHASTAR.
'Ensuring sponsor oversight, and quality of data and interpretation for early phase trials' by Dr Susan Lovick, Statistical Technical Lead - PHASTAR.
The event will take place on Tuesday 26th November, 9:30am-4pm at the Alderley Park Conference Centre. Registration will start at 9:30am and the sessions will run from 10am-4pm, followed by a networking reception at 4pm-6pm.
If you are interested in attending sign up is free and can be found here!
Traditionally, studies have been run with a process of study design, study conduct, study report. Whilst this is more straight-forward it is not flexible and does not allow for modifications or changes that may be desirable during the course of a trial. An adaptive design allows for the flexibility of interim reviews of the data, followed by pre-specified changes to the trial based on the review whilst maintaining the integrity of the trial, interim reviews may also result in outcomes such as a sample size re-estimation These prior planned adaptations are different to ad hoc protocol amendments, as the adaptations are already allowed for in the protocol.
The volume of digital data in healthcare is projected to increase more rapidly in the coming years than any other sector. On a day-to-day basis it is vital that clinical teams ensure they are maximising the value, not only of their own trial data but also of the wealth of external data for example electronic healthcare records, real-world data and peer-reviewed research published in journals.
The ability to utilise this data requires not only an understanding of what is available but how to access the data, work with the structure of the data, understand the quality and inherent biases and importantly apply the right methodology to extract value. In addition to the large volume of standard data generated on a clinical trial there can be a raft of other, more specialised data, such as genomics, proteomics, wearables and comprehensive measurements all of which rely on the skills of an experienced data management, programming and statistics team to utilise.
Showcasing the varied technical abilities of programmers, statisticians and data scientists within PHASTAR, the company has had a number of papers chosen for presentation at the PhUSE EU Connect conference in Amsterdam (10-13th November 2019). A total of 8 oral presentations and 2 posters will cover topics from a diverse set of areas that include: Analytical Risk-based Monitoring, Application Development, Coding Tips & Tricks, Data Standards and Governance, Real-world Evidence, Scripts & Macros and Standards Implementation.